Products

CELLAVISTA 4®

CELLAVISTA 4 is a fully automated cell imager with unsurpassed speed and superb image quality. Designed for medium to high-throughput laboratory settings, it features brightfield and optional multiple fluorescence channels. The versatile CELLAVISTA 4 is ideal for high-content screening (HCS), single cell cloning, cell counting, and so much more.

Features
  • Ultrafast multiplex imaging – full scan of a 96-well microplate at 10x magnification in 3-4 minutes.
  • Versatile system that currently supports over 60 applications for cell line development, cancer research, stem cell research, preclinical drug development, virology, immunology and cell biology.
  • Brightfield + up to six fluorescence channels within the visible spectrum from UV to Red .
  • High resolution images- highly sensitive optics and HCS-grade lenses.
  • Equipped with up to 5 different magnifications.
  • Fast parallel image processing.
  • Automated laser-based autofocusing.
  • Compatible with a wide range of SDS format microplates ranging from 6 to 1536 wells, dishes, T-25 flasks and microscope slides.
  • Intuitive SYNENTEC’s YT software with comprehensive graphical output.
  • Excellent well edge illumination of microplates.
  • Perfect image stitching.
  • Built-in interface enabling integration with SYNENTEC’s SYBOT-1000 automated plate handler or into robotic platforms from Hamilton, Tecan, Beckman Coulter, PAA, Perkin Elmer, ThermoFisher and others.
  • Capable of imaging over 250 microplates per day in automated environments.

Models:

CELLAVISTA 4® comes in 3 different models:

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Featured Applications:

CELLAVISTA 4® is a very versatile system that can be used for over 60 applications in cell line development, cancer, stem cell, preclinical drug development, immunology, and cell biology labs. Its ultra-fast multiplex imaging is ideal for high-content screening (HCS). The list of applications includes:
Other Applications
  • Automated Multiplex Cell Imaging
  • Antibody Binding Assays
  • Monitoring Transfection Efficiency in Situ
  • Crispr/CAS Gene Editing
  • Immunocytochemistry (ICC/IHC)
  • Stem Cells, iPS Cell Characterization and Monitoring
  • Live/Dead Cytotoxicity Assay
  • Cell Apoptosis (Annexin V, JC-1, caspases)
  • DNA Damage
  • Nuclei Staining
  • Cell Cycle and Mitosis Analysis
  • Rare Cell Identification (CTC, circulating tumor cells)
  • Immunological Staining of CD Markers
  • Antibody and ADC Internalization Assays
  • siRNA Detection
  • Oxidative Stress (ROS)
  • IgG and Glycan Quantification (in combination with PAIA plates)
  • FASC Seeding Control
  • For a full list of applications, protocols, and technical notes, please visit Synentec’s website.

NyONE®

NyONE is a fast, compact, automated cell imager that is ideal for small to medium throughput labs. It combines brightfield and optional fluorescence microscopy. It is the perfect system for single cell cloning to confirm monoclonality, fast cell imaging, cell counting with viability (96 samples in less than 3 minutes), and many other applications utilizing automated fluorescence microscopy.

Features
  • Performs automated, fast, and non-invasive brightfield and fluorescence imaging with multi-parameter image analysis
  • Versatile, dozens of applications for cell line development, cancer research, stem cell research, preclinical drug development, virology, immunology, and cell biology labs
  • Full scan of a 96-well microplate at 10x magnification in less than 6 minutes
  • Brightfield imaging + optional 3 or 4 fluorescence channels
  • High resolution, high quality images
  • Fast parallel image processing
  • Automated laser-based autofocusing
  • Compatible with a wide range of SDS format microplates ranging from 6 to 1536 wells, dishes, T-25 flasks and microscope slides.
  • Works with both adherent and suspension cells 
  • Intuitive SYNENTEC’s YT-software with comprehensive graphical output
  • Excellent well edge illumination of microplates
  • Perfect image stitching
  • Built-in interface enabling integration into robotic platforms
  • Can be accompanied with Synentec’s SyBOT-800 automated system or linked to robotic systems from companies like Hamilton, Tecan, Perkin Elmer, Beckman Coulter, PAA, ThermoFisher, and others
  • In automated environments, NyONE is capable of imaging over 100 microplates per day.

Featured Models:

NyONE CLD HIGH END®
NYONE CLD HIGH END is equipped with 3 different lenses, achieving resolutions down to 360 nm/pixel, 3-4 excitation sources (UV to RED) and up to 6 different emission filters. All operating procedures are fully automated and can be embedded into a completely automated environment.

NYONE SCIENTIFIC®
NYONE SCIENTIFIC is a brand new model with a highly sensitive 16-bit sCMOS camera and high numeric aperture lenses for measuring wider ranges of signal intensities, a higher dynamic range, and a better signal to background ratio.

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Featured Applications:

NYONE® is a very versatile system that can be used for dozens of applications in cell line development, basic and translational research, and preclinical drug development.

Other Applications

  • Automated Multiplex Cell Imaging
  • Antibody Binding Assays
  • Monitoring Transfection Efficiency in Situ
  • Crispr/CAS Gene Editing
  • Immunocytochemistry (ICC/IHC)
  • Stem Cells, iPS Cell Characterization and Monitoring
  • Live/Dead Cytotoxicity Assay
  • Cell Apoptosis (Annexin V, JC-1, caspases)
  • DNA Damage
  • Nuclei Staining
  • Cell Cycle and Mitosis Analysis
  • Rare Cell Identification (CTC, circulating tumor cells)
  • Immunological Staining of CD Markers
  • Antibody and ADC Internalization Assays
  • siRNA Detection
  • Oxidative Stress (ROS)
  • IgG and Glycan Quantification (in combination with PAIA plates)
  • FASC Seeding Control
  • For a complete list of applications and technical notes, please visit SYNENTEC’s website

SYBOT-1000

SYNENTEC announces the release of its new automated plate handler, the SYBOT-1000. It is specially adapted for SYNENTEC’s automated imaging systems CELLAVISTA® and NYONE® , and completely integrates into SYNENTEC’s YT-software.

Features
  • Designed to meet high-throughput demands and increase walk-away time.
  • All 60+ applications from our portfolio can be automated with SYBOT-1000.
  • SYBOT-1000 automated plate handler provides various levels of automation:
  • Simple plate loading at ambient temperatures.
  • Integration with liquid handlers, cell printers, and clone pickers.
  • Integrating imaging with the CytomatTM 2 C-LiN incubator.
  • High-end integrations with external collaborators into cutting edge automation enclosures: PAA Automation, Hamilton Robotics, Tecan Group, Analytic Jena, Beckman Coulter, Thermo Fisher Scientific, Perkin Elmer (Caliper Life Sciences), Biosero, HighRes Biosolutions

For more details about this and other SYNENTEC’s systems, visit SYNENTEC’s website

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